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My Cart> Antibodies > Primary Antibodies > Anti-GPR37L1 Polyclonal AntibodySAlexa Fluor 350Reactivity：Human
Application：SAlexa Fluor 350
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：9283
Host：Rabbit
Qty：
Size：
| Reactivity | Human |
| Background | G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade. However, other studies have shown that prosaposin does not increase activit. It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha. Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway. Regulates baseline blood pressure in females and protects against cardiovascular stress in males. Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity. |
| Subtype | IgG |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Host | Rabbit |
| Application | WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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Note：
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