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My Cart> Antibodies > Primary Antibodies > Anti-MLKL Monoclonal AntibodySAlexa Fluor 350Reactivity：Mouse,Human
Application：SAlexa Fluor 350
Clone Type：Monoclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：197259
Host：Mouse
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| Reactivity | Mouse,Human |
| Background | Mixed lineage kinase domain like pseudokinase (MLKL), belongs to the protein kinase superfamily, has two MW of 54 and 30 kDa. MLKL plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. 66675-1-Ig antibody recognizes 54 kDa MLKL monomer, 216 kDa MLKL tetramer and a band around 45-50 kDa which are similar to papers published. (PMID: 31848291) |
| Subtype | IgG1 |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Host | Mouse |
| Application | ELISA IF IHC WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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Note：
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