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My Cart> Antibodies > Primary Antibodies > Anti-ZNF131 Polyclonal AntibodySAlexa Fluor 633Reactivity：Human,Rat,Mouse
Application：SAlexa Fluor 633
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：7690
Host：Rabbit
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| Reactivity | Human,Rat,Mouse |
| Background | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF131 (Zinc finger protein 131) is a 623 amino acid nuclear protein that contains one BTB (POZ) domain and six C2H2-type zinc fingers. With predominant expression found in brain, it is likely that ZNF131 plays a role as a transcription regulator during development and organogenesis of the adult central nervous system. ZNF131 also represses ER (Estrogen receptor alpha)-mediated transactivation by interrupting ER binding to the estrogen-response element. There are two isoforms of ZNF131 that are produced as a result of alternative splicing events. |
| Subtype | IgG |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Host | Rabbit |
| Application | ELISA IHC WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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