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My Cart> Antibodies > Primary Antibodies > Anti-NFkB p105/p50 Monoclonal AntibodySAlexa Fluor 640Reactivity：Human,Rat,Mouse
Application：SAlexa Fluor 640
Clone Type：Monoclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：4790
Host：Rabbit
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| Reactivity | Human,Rat,Mouse |
| Background | Proteins encoded by the v-Rel viral oncogene and its cellular homolog，c-Rel，are members of a family of transcription factors that include the two subunits of the transcription factor NFkB (p50 and p65) and the Drosophila maternal morphagen，dorsal. These proteins share sequence homology over a region of 300 amino acids at their NH2-terminus，the region that contains their DNA binding and dimerization domains. The DNA binding activity of NF B is activated and rapidly transported from the cytoplasm to the nucleus in cells exposed to mitogens or growth factors. cDNAs encoding precursors for two distinct proteins have been described. These proteins，designated p105 and p100，are highly related but map on different chromosomes. The p105 (p110) precursor contains p50 at its N-terminus and a C-terminal region that when expressed as a separate molecule，designated PdI，binds to p50 and regulates its activity. |
| Subtype | IgG |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Host | Rabbit |
| Application | WB FCM IF IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
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