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My Cart> Antibodies > Primary Antibodies > Anti-MHC Class II(FITC) Monoclonal AntibodyCy7Reactivity：Mouse
Application：Cy7
Clone Type：Monoclonal Antibody
Storage：Store at 2-8℃. Avoid exposure to light.
Gene ID：14960
Host：Rat
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| Reactivity | Mouse |
| Background | Major histocompatibility complex (MHC) class II molecules are heterodimeric transmembrane glycoproteins that are expressed on the surface of antigen-presenting cells such as dendritic cells， macrophages， and B cells. The M5/114.15.2 antibody detects polymorphic determinants present on B cells， monocytes， macrophages， dendritic cells， and activated T lymphocytes from mice carrying the H-2b， H-2d， H-2q， H-2p， H-2r and H-2u haplotypes but not from mice carrying the H-2s or H-2f haplotypes (PMID: 6170707). This antibody recognizes both I-A and I-E subregion-encoded Ia glycoproteins (I-Ab， I-Ad， I-Aq， I-Ed， I-Ek， not I-Af， I-Ak， or I-As). M5/114 mAb is reported to inhibit I-A subregion-restricted T cell responses of the H-2b， H-2d， H-2q， H-2u but not the H-2f， H-2k， H-2s haplotypes (PMID: 6173436). |
| Subtype | IgG2b |
| Storage | Store at 2-8℃. Avoid exposure to light. |
| Host | Rat |
| Application | FCM |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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