{{cart_num}}
My CartReactivity：Rat,Mouse,Human
Application：IHC,WB,ELISA,IF,ICC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：30837
Host：Rabbit
Qty：
Size：
| Name | Anti-SOCS7 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Predicted Reactivity | Rabbit |
| Dilution Ratio | WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. ICC 1:100-500. IF 1:100-500. |
| Target | SOCS7 |
| Background | Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
| Swiss Prot | O14512 |
| Gene ID | 30837 |
| Subcellular Location | Cell membrane Cytoplasm |
| Immunogen | A synthetic peptide of human SOCS7 |
| Public Immunogen Range | 171-270/581aa |
| Calculated MW | 63kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 0.03% Proclin300，50% glycerol，pH7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | Rat Mouse Human |
| Application | ELISA IF ICC IHC WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with SOCS7 antibody diluted at 1:1000;Lane: Mouse Cerebrum Mouse Cerebellum Mouse Testis Mouse Stomach Mouse Placenta Rat Cerebrum Rat Cerebellum Rat testis HepG2 Hela MCF-7 HL60 Molt-4.
Immunohistochemistry of paraffin-embedded Mouse embryo tissue with SOCS7 antibody diluted at 1:200
Immunohistochemistry of paraffin-embedded Mouse embryo tissue with SOCS7 antibody diluted at 1:500.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
