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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > 4-Cholesten-3-oneCAS：601-57-0
Molecular Formula：C27H44O
Molecular Weight：384.64
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 601-57-0 |
| Name | 4-Cholesten-3-one |
| Molecular Formula | C27H44O |
| Molecular Weight | 384.64 |
| Solubility | Soluble in Ethanol |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 210-005-1 |
| MDL | MFCD00003663 |
| SMILES | CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O |
| InChIKey | NYOXRYYXRWJDKP-GYKMGIIDSA-N |
| InChI | InChI=1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h17-19,22-25H,6-16H2,1-5H3/t19-,22+,23-,24+,25+,26+,27-/m1/s1 |
| PubChem CID | 91477 |
| Target Point | Others |
| Passage | Others |
| Background | It is an intermediate oxidation product of cholesterol, which is highly mobile in membranes and affects the turnover and efflux of cholesterol. |
| Biological Activity | Cholestenone (4-Cholesten-3-one)， the intermediate oxidation product of cholesterol， is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells[1-2]. |
| Data Literature Source | [1]. Rosenheim O，et al. The mechanism of coprosterol formation in vivo: 1. Cholestenone as an intermediate. Biochem J. 1943 Oct;37(4):513-4. [2]. Neuvonen M，et，al. Enzymatic oxidation of cholesterol: properties and functional effects of cholestenone in cell membranes. PLoS One. 2014 Aug 26;9(8):e103743. |
| Unit | Bottle |
| Specification | 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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