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My Cart> Peptides > Substrate and Enzyme Inhibitors > PKC Substrate [RRGR-pT-GRGRRGIFR], PhosphorylatedMolecular Formula：C69H126N35O19P1
Molecular Weight：1780.96
Purity：≥95%
Appearance：Lyophilized powder
Storage：Store at -20℃，2 years.(Avoid freeze/thaw cycles)
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| Product Type | Peptides |
| Sequence(1LC) | RRGR-pT-GRGRRGIFR |
| Sequence(3LC) | Arg-Arg-Gly-Arg-pThr-Gly-Arg-Gly-Arg-Arg-Gly-Ile-Phe-Arg |
| Molecular Formula | C69H126N35O19P1 |
| Molecular Weight | 1780.96 |
| Purity | ≥95% |
| Appearance | Lyophilized powder |
| Salt Form | Trifluoroacetate salt |
| Source | Synthetic |
| Storage | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| Category/Label | Substrate and Enzyme Inhibitors |
| Background | The native peptide, RRGRTGRGRRGIF, is proven to be a highly selective substrate for Protein Kinase C (PKC). It is based on the amino acid sequence 1487-1500 of the non-structural protein 3 of Hepatitis C virus (HCV). Substitution of Tyr1499 in HCV by Phe makes the peptide substrate more effectively phosphorylated by rat brain PKC (Km = 5μM) and mouse epidermal cell extracts (Km = 25 nM) than other kinases such as tyrosine kinases or other serine/threonine kinases. It is very useful for assaying PKC activity in the presence of other kinases in tissues and crude cell extracts. |
| Reference | [1] Borowski, P. et al. J. Biol. Chem. 274, 30722 (1999). |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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