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My Cart> Antibodies > Primary Antibodies > Anti-Glutamate receptor 3 Polyclonal AntibodyReactivity：Human
Application：IHC,ELISA,IF
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：2892
Host：Rabbit
Qty：
Size：
| Name | Anti-Glutamate receptor 3 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Predicted Reactivity | Mouse;Rat;Dog;Pig;Cow;Horse;Rabbit |
| Dilution Ratio | IHC 1:100-500.;IF 1:100-500.;ELISA 1:5000-10000. |
| Target | GLUR3 |
| Background | L-Glutamate is the major excitatory neurotransmitter in the mammalian CNS, acting through both ligand gated ion channels (ionotropic receptors) and G-protein coupled (metabotropic) receptors. As such the glutamate receptors play a vital role in the mediation of excitatory synaptic transmission. The ionotropic glutamate receptors are multimeric assemblies of four or five subunits, and are subdivided into three groups (AMPA, NMDA and Kainate receptors) based on their pharmacology structural similarities Glutamate Receptor 3 is a ionotropic, AMPA-selective, membrane bound protein widely distributed in the CNS. Predominant expression is seen in the neuronal cells of the cerebral cortex, dentate gyrus, and glial cells throughout brain regions. AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. Glutamate Receptor 3 exists in 2 named isoforms - Flip and Flop, produced by alternative splicing. |
| Swiss Prot | P42263 |
| Gene ID | 2892 |
| Subcellular Location | Cell junction Cell membrane Multi-pass membrane protein postsynaptic cell membrane synapse |
| Immunogen | KLH conjugated synthetic peptide derived from human GLUR3 |
| Public Immunogen Range | 451-550/894aa |
| Calculated MW | 98kDa |
| Purification Method | Affinity purification |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA，0.03% Proclin300 and 50% Glycerol. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | Human |
| Application | ELISA IF IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Immunohistochemistry of paraffin-embedded Human breast cancer with GLUR3 antibody diluted at 1:400
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