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My CartReactivity：Rat,Human,Mouse
Application：IHC,WB
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：11160
Host：Rabbit
Qty：
Size：
| Name | Anti-ERLIN2 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Predicted Reactivity | Bovine; Orangutan; Zebrafish |
| Dilution Ratio | WB 1:1000-3000.; IHC 1:50-200. |
| Target | ERLIN2 |
| Background | Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1. Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex. |
| Swiss Prot | O94905 |
| Gene ID | 11160 |
| Subcellular Location | Cytoplasm |
| Immunogen | Recombinant protein of human ERLIN2 |
| Public Immunogen Range | 1-153aa |
| Calculated MW | 17/23/38kDa |
| Purification Method | Octanoic acid-ammonium sulfate precipitation |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Y-Dilution Ratio | WB 1:1000-3000. IHC 1:50-200. |
| Specification | 20ul 50ul 100ul |
| Reactivity | Rat Human Mouse |
| Application | WB IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with ERLIN2 antibody diluted at 1:2000;Lane: 293T.
Immunohistochemistry of paraffin-embedded Human breast cancer with ERLIN2 antibody diluted at 1:100.
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