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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > L-KynurenineCAS：2922-83-0
Molecular Formula：C10H12N2O3
Molecular Weight：208.22
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to yellow Solid
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| CAS | 2922-83-0 |
| Name | L-Kynurenine |
| Molecular Formula | C10H12N2O3 |
| Molecular Weight | 208.22 |
| Solubility | Soluble in DMSO ≥5mg/mL(Need ultrasonic) |
| Purity | HPLC≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00069912 |
| SMILES | O=C(O)[C@@H](N)CC(C1=CC=CC=C1N)=O |
| Target Point | Aryl Hydrocarbon Receptor |
| Passage | Immunology & Inflammation |
| Background | It is an aryl hydrocarbon receptor agonist. |
| Data Literature Source | [1]. Moyer BJ，et al. Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL，TLR2/4，TGFβ，and IDO1. Toxicol Appl Pharmacol. 2016 Jun 1;300:13-24. [2]. Sakakibara K，et al. Kynurenine causes vasodilation and hypotension induced by activation of KCNQ-encoded voltage-dependent K(+) channels. J Pharmacol Sci. 2015 Sep;129(1):31-7. [3]. Nozaki K，et al. Neuroprotective effects of L-kynurenine on hypoxia-ischemia and NMDA lesions in neonatal rats. J Cereb Blood Flow Metab. 1992 May;12(3):400-7. |
| Unit | Bottle |
| Specification | 10mg 10mM*1mL in DMSO 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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