{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > NF-κB > BAY-11-7085CAS：196309-76-9
Molecular Formula：C13H15NO2S
Molecular Weight：249.33
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 196309-76-9 |
| Name | BAY-11-7085 |
| Molecular Formula | C13H15NO2S |
| Molecular Weight | 249.33 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD01862602 |
| SMILES | CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)/C=C/C#N |
| Target Point | NF-κB |
| Passage | NF-κB |
| Background | It is an inhibitor of NF-κB activation and IκBα phosphorylation. |
| Biological Activity | BAY 11-7085是NF-κB激活和IκBα磷酸化的抑制剂，稳定IκBα的IC50值为10 μM。[1-2] |
| Data Literature Source | [1]. Pierce JW，et al. Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesionmolecule expression show anti-inflammatory effects in vivo. J Biol Chem. 1997 Aug 22;272(34):21096-103. [2]. Nasu K，et al. Application of the nuclear factor-kappaB inhibitor BAY 11-7085 for the treatment of endometriosis: an in vitro study. Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E16-23. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
