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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > PI3K/Akt/mTOR > AZD-8835CAS：1620576-64-8
Molecular Formula：C22H31N9O3
Molecular Weight：469.54
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 1620576-64-8 |
| Name | AZD-8835 |
| Molecular Formula | C22H31N9O3 |
| Molecular Weight | 469.54 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 829-551-2 |
| MDL | MFCD28902194 |
| SMILES | O=C(N1CCC(C2=NN(CC)C(C3=NC(C4=NN=C(C(C)(C)C)O4)=C(N)N=C3)=N2)CC1)CCO |
| Target Point | PI3K |
| Passage | PI3K/Akt/mTOR |
| Background | AZD-8835 is a potent and selective PI3Kα and PI3Kδ inhibitor. |
| Biological Activity | AZD8835是一种新型的PI3Kα和PI3Kδ混合型抑制剂，IC50分别为6.2 nM和5.7 nM。对PI3Kβ和PI3Kγ同样具有选择性，IC50分别为431 nM和90 nM。[2] |
| Data Literature Source | [1] Hudson K，et al. Mol Cancer Ther. 2016，15(5):877-89. [2] Bernard Barlaam，et al. Bioorganic & Medicinal Chemistry Lette |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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