{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > PI3K/Akt/mTOR > SapanisertibCAS：1224844-38-5
Molecular Formula：C15H15N7O
Molecular Weight：309.33
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 1224844-38-5 |
| Name | Sapanisertib |
| Molecular Formula | C15H15N7O |
| Molecular Weight | 309.33 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD22124893 |
| SMILES | CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=C(C=C3)OC(=N4)N)N |
| Target Point | mTOR |
| Passage | PI3K/Akt/mTOR |
| Background | It is an orally active ATP-dependent mTOR1/2 inhibitor. |
| Biological Activity | Sapanisertib (INK-128) 是ATP依赖性的 mTOR1/2 抑制剂，抑制mTOR激酶的IC50 值为1 nM。[1-2] |
| Data Literature Source | [1]. Liu A，et al. mTOR Mediated Anti-Cancer Drug Discovery. Drug Discovery Today: Therapeutic Strategies. 2009，6(2)，47-55. [2]. Hsieh AC，et al. The translational landscape of mTOR signalling steers cancer initiation and metastasis. Nature. 2012 Feb 22;485(7396):55-61 |
| Unit | Bottle |
| Specification | 5mg 10mg 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
