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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > EnasidenibCAS：1446502-11-9
Molecular Formula：C19H17F6N7O
Molecular Weight：473.38
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1446502-11-9 |
| Name | Enasidenib |
| Molecular Formula | C19H17F6N7O |
| Molecular Weight | 473.38 |
| Solubility | Soluble in DMSO ≥10mg/mL;Soluble in Water ＜ 1mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD29472245 |
| SMILES | CC(O)(C)CNC1=NC(C2=NC(C(F)(F)F)=CC=C2)=NC(NC3=CC(C(F)(F)F)=NC=C3)=N1 |
| Target Point | IDH2 (Isocitrate dehydrogenase 2) |
| Passage | Metabolic Enzyme&Protease |
| Background | It is a novel potent and selective reversible inhibitor of IDH2 mutant enzymes. |
| Biological Activity | Enasidenib (AG-221) 是一种新型有效的、具有选择性的IDH2突变酶的可逆抑制剂。[1] |
| Data Literature Source | [1] Alan H. Shih，et al. Blood. 2014，124:437. [2] Kate Ellwood-Yen，et al. AACR. 2014，74(19 Sup.):3116. |
| Unit | Bottle |
| Specification | 2mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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