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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > AceclofenacCAS：89796-99-6
Molecular Formula：C16H13Cl2NO4
Molecular Weight：354.18
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 89796-99-6 |
| Name | Aceclofenac |
| Molecular Formula | C16H13Cl2NO4 |
| Molecular Weight | 354.18 |
| Solubility | Soluble in DMSO/Ethanol ≥10mg/mL;Soluble in Water < 1mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 205-783-4 |
| MDL | MFCD00864296 |
| SMILES | O=C(OCC(O)=O)CC1=CC=CC=C1NC2=C(Cl)C=CC=C2Cl |
| Target Point | COX2 |
| Passage | Immunology & Inflammation |
| Background | It is a cyclooxygenase 2 inhibitor that can be used in the related research of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. |
| Biological Activity | Aceclofenac is an orally active nonsteroidal anti-inflammatory drug (NSAID)， with analgesic and anti-inflammatory properties. Aceclofenac is used for the research of osteoarthritis， ankylosing spondylitis， rheumatoid arthritis[1-2]. |
| Data Literature Source | [1]. Y Henrotin，et al. In vitro effects of aceclofenac and its metabolites on the production by chondrocytes of inflammatory mediators. Inflamm Res. 2001 Aug;50(8):391-9. [2]. E Maneiro，et al. Aceclofenac increases the synthesis of interleukin 1 receptor antagonist and decreases the production of nitric oxide in human articular chondrocytes. J Rheumatol. 2001 Dec;28(12):2692-9. [3]. E Maneiro，et al. Keumhan Noh，et al. Absolute bioavailability and metabolism of aceclofenac in rats. Arch Pharm Res. 2015 Jan;38(1):68-72. |
| Unit | Bottle |
| Specification | 200mg 500mg 1g |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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