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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Epigenetics > Menin-MLL inhibitor MI-2CAS：1271738-62-5
Molecular Formula：C18H25N5S2
Molecular Weight：375.55
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 1271738-62-5 |
| Name | Menin-MLL inhibitor MI-2 |
| Molecular Formula | C18H25N5S2 |
| Molecular Weight | 375.55 |
| Solubility | Soluble in DMSO ≥5mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD22575021 |
| SMILES | CCCC1=CC2=C(N3CCN(C4=NCC(C)(C)S4)CC3)N=CN=C2S1 |
| Target Point | Menin-MLL interaction |
| Passage | Epigenetics |
| Background | It is a potent inhibitor of menin-mLL interaction. |
| Biological Activity | MI-2 抑制 Menin-MLL 相互作用，IC50 为 446±28 nM。[1] |
| IC50 | 446±28nM(Menin-MLL)[1] |
| Data Literature Source | [1]. Grembecka J，et al. Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia. Nature Chemical Biology (2012)，8(3)，277-284 |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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