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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > ER Stress > 8-Formyl-7-Hydroxy-4-Methyl-CoumarinCAS：14003-96-4
Molecular Formula：C11H8O4
Molecular Weight：204.18
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 14003-96-4 |
| Name | 8-Formyl-7-Hydroxy-4-Methyl-Coumarin |
| Molecular Formula | C11H8O4 |
| Molecular Weight | 204.18 |
| Solubility | Soluble in DMSO ≥2mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD12027255 |
| SMILES | O=CC1=C(O)C=CC2=C1OC(C=C2C)=O |
| Target Point | IRE1 |
| Passage | ER Stress |
| Background | It is a potent and selective IRE1 RNAse inhibitor. |
| Biological Activity | 4μ8C (IRE1 Inhibitor III)是高效的选择性IRE1 Rnase抑制剂，IC50为76 nM。[1] |
| IC50 | IRE1 Rnase：76nM[1] |
| Data Literature Source | [1] Cross BC，et al. Proc Natl Acad Sci U S A. 2012，109(15)，E869-878. [2] Kemp KL，et al. J Biol Chem. 2013，288(46)，33272-33282. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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