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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > PACAP-1-38CAS：137061-48-4
Molecular Formula：C203H331N63O53S
Molecular Weight：4534.26
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥96%
Appearance：White to off-white Solid
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| CAS | 137061-48-4 |
| Name | PACAP-1-38 |
| Molecular Formula | C203H331N63O53S |
| Molecular Weight | 4534.26 |
| Solubility | Soluble in Water |
| Purity | ≥96% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00081800 |
| SMILES | --- |
| Target Point | PACAP receptor |
| Passage | Others |
| Background | H-Gly-Gly-Pro-OH is a polypeptide consisting of 3 amino acids. |
| Biological Activity | PACAP (1-38), human, ovine, rat is a neuropeptide with 38 amino acid residues. PACAP (1-38) binds to PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2 with IC50s of 4 nM, 2 nM, and 1 nM, respectively.[1-4] |
| IC50 | 4nM(PACAP type I receptor);2nM(PACAP type II receptor VIP1);1nM(PACAP type II receptor VIP2)[1] |
| Data Literature Source | [1]. Gourlet P，et al. Fragments of pituitary adenylate cyclase activating polypeptide discriminate between type I and II recombinant receptors. Eur J Pharmacol. 1995 Dec 4;287(1):7-11. [2]. Yamaguchi N. Pituitary adenylate cyclase activating polypeptide enhances glucose-evoked insulin secretion in the canine pancreas in vivo. JOP. 2001 Sep;2(5):306-16. [3]. Lindén A，et al. Inhibition of bronchoconstriction by pituitary adenylate cyclase activating polypeptide (PACAP 1-27) in guinea-pigs in vivo. Br J Pharmacol. 1995 Jul;115(6):913-6. [4]. Werling D，et al. Passage through the Ocular Barriers and Beneficial Effects in Retinal Ischemia of Topical Application of PACAP (1-38) in Rodents. Int J Mol Sci. 2017 Mar 21;18(3). pii: E675. |
| Unit | Bottle |
| Specification | 1mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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