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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > GPCR & G Protein > Otenabant HydrochlorideCAS：686347-12-6
Molecular Formula：C25H25Cl2N7O·HCl
Molecular Weight：546.88
Storage：Powder:2-8℃，2 years
Purity：≥98%
Appearance：White to yellow Solid
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| CAS | 686347-12-6 |
| Name | Otenabant Hydrochloride |
| Molecular Formula | C25H25Cl2N7O·HCl |
| Molecular Weight | 546.88 |
| Solubility | Soluble in --- |
| Purity | ≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years |
| MDL | MFCD18251544 |
| SMILES | [H]Cl.ClC1=CC=CC=C1C2=NC3=C(N4CCC(NCC)(C(N)=O)CC4)N=CN=C3N2C5=CC=C(Cl)C=C5 |
| Target Point | Cannabinoid Receptor |
| Passage | GPCR & G Protein;Neuronal Signaling |
| Background | It is a high-affinity antagonist of CB1 receptors. |
| Biological Activity | Otenabant (CP945598)盐酸盐是CB1受体高亲和性拮抗剂，Ki为0.7 nM。[1-2] |
| Data Literature Source | [1]. John R. Hadcock，et al. In vitro and in vivo pharmacology of CP-945，598，a potent and selective cannabinoid CB1 receptor antagonist for the management of obesity. Biochemical and Biophysical Research Communications，2010; 394;366-371. [2]. Griffith DA，et al. Discovery of 1-[9-(4-chlorophenyl) -8-(2-chlorophenyl)- 9H-purin-6-yl] -4-ethylaminopiperidine-4-carboxylic acid amide hydrochloride (CP-945，598)，a novel，potent，and selective cannabinoid type 1 receptor antagonist. JMedChem. 2009 ;5 |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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