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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > MAPK > CEP-32496CAS：1188910-76-0
Molecular Formula：C24H22F3N5O5
Molecular Weight：517.46
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1188910-76-0 |
| Name | CEP-32496 |
| Molecular Formula | C24H22F3N5O5 |
| Molecular Weight | 517.46 |
| Solubility | Soluble in DMSO ≥1mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD22124524 |
| SMILES | O=C(NC1=NOC(C(C)(C)C(F)(F)F)=C1)NC2=CC=CC(OC3=C(C=C(OC)C(OC)=C4)C4=NC=N3)=C2 |
| Target Point | Raf |
| Passage | MAPK |
| Background | CEP-32496 is a BRAF inhibitor. |
| Biological Activity | CEP-32496 是一种口服高效的 BRAFV600E 抑制剂，Kd 为 14 nM。[1] |
| Data Literature Source | [1]. Rowbottom MW，et al. Identification of 1-(3-(6，7-dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1，1，1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea hydrochloride (CEP-32496)，a highly potent and orally efficacious inhibitor of V-RAF murine sarcoma viral oncogene homologue B1 (BRAF) V600E |
| Unit | Bottle |
| Specification | 2mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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