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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > JAK/STAT > BMS-911543CAS：1271022-90-2
Molecular Formula：C23H28N8O
Molecular Weight：432.52
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to yellow Solid
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| CAS | 1271022-90-2 |
| Name | BMS-911543 |
| Molecular Formula | C23H28N8O |
| Molecular Weight | 432.52 |
| Solubility | Soluble in DMSO ≥5mg/mL;Soluble in Water ＜ 0.1mg/mL |
| Purity | ≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 1308068-626-2 |
| MDL | MFCD22200575 |
| SMILES | O=C(C1=CC2=C(N(C)C=N3)C3=C(NC4=NN(C)C(C)=C4)N=C2N1CC)N(C5CC5)C6CC6 |
| Target Point | JAK |
| Passage | JAK/STAT Signaling |
| Background | BMS-911543 is a potent and selective JAK2 inhibitor |
| Biological Activity | BMS-911543是一种有效的、选择性JAK2小分子抑制剂，IC50为1.1 nM。[1] |
| IC50 | JAK2(Cell-free assay):1.1nM[1] |
| Data Literature Source | [1] Wan H，et al. ACS Med Chem Lett. 2015，6(8):850-5. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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