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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > BI-847325CAS：1207293-36-4
Molecular Formula：C29H28N4O2
Molecular Weight：464.56
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 1207293-36-4 |
| Name | BI-847325 |
| Molecular Formula | C29H28N4O2 |
| Molecular Weight | 464.56 |
| Solubility | Soluble in DMSO ≥2mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD28978743 |
| SMILES | O=C(NCC)C#CC1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC=C(CN(C)C)C=C3)/C4=CC=CC=C4 |
| Target Point | MEK，Aurora Kinase |
| Passage | Cell Cycle |
| Background | BI-847325 is a novel, potent and selective dual inhibitor of MEK and Aurora kinases |
| Biological Activity | BI-847325是一种口服具有生物活性的选择性的双重MEK/Aurora kinase抑制剂，对非洲爪蟾Aurora B，人Aurora A 和Aurora C，以及人MEK1 和MEK2的IC50分别为3 nM，25 nM，15 nM，25 nM，和4 nM。[1] |
| Data Literature Source | [1] Phadke MS，et al. Mol Cancer Ther. 2015，14(6)，1354-1364. |
| Unit | Bottle |
| Specification | 1mg 2mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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