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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > A-922500CAS：959122-11-3
Molecular Formula：C26H24N2O4
Molecular Weight：428.48
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to orange Solid
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| CAS | 959122-11-3 |
| Name | A-922500 |
| Molecular Formula | C26H24N2O4 |
| Molecular Weight | 428.48 |
| Solubility | Soluble in DMSO ≥5mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Light yellow to orange Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD12828780 |
| SMILES | O=C(NC1=CC=C(C2=CC=C(C([C@@H]3CCC[C@H]3C(O)=O)=O)C=C2)C=C1)NC4=CC=CC=C4 |
| Target Point | DGAT-1 |
| Passage | Metabolic Enzyme&Protease |
| Background | A-922500 is a potent and selective DGAT-1 inhibitor. |
| Biological Activity | A 922500是一种有效，选择性和口服可用的 DGAT-1 抑制剂，抑制小鼠和人DGAT-1的IC50s 分别为 9，22 nM。 |
| IC50 | 9nM(human DGAT-1)，22nM(mouse DGAT-1)[1] |
| Data Literature Source | [1]. King AJ，et al. Diacylglycerol acyltransferase 1 inhibition lowers serum triglycerides in the Zucker fatty rat and the hyperlipidemic hamster. J Pharmacol Exp Ther. 2009 Aug;330(2):526-31. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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