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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > NF-κB > 4-Octyl ItaconateCAS：3133-16-2
Molecular Formula：C13H22O4
Molecular Weight：242.31
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 3133-16-2 |
| Name | 4-Octyl Itaconate |
| Molecular Formula | C13H22O4 |
| Molecular Weight | 242.31 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD31706409 |
| SMILES | O=C(OCCCCCCCC)CC(C(O)=O)=C |
| Target Point | Keap1-Nrf2 |
| Passage | NF-κB |
| Background | 4-Octyl Itaconate is an anti-inflammatory metabolite that activates Nrf2 through the alkylation of Keap1. |
| Biological Activity | 4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1[1]. |
| Data Literature Source | [1]. Mills EL，et al. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature. 2018 Apr 5;556(7699):113-117. |
| Unit | Bottle |
| Specification | 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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