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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > MAPK > SCH-772984CAS：942183-80-4
Molecular Formula：C33H33N9O2
Molecular Weight：587.67
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 942183-80-4 |
| Name | SCH-772984 |
| Molecular Formula | C33H33N9O2 |
| Molecular Weight | 587.67 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 1592732-453-0 |
| MDL | MFCD28144700 |
| SMILES | O=C([C@H](CC1)CN1CC(N(CC2)CCN2C(C=C3)=CC=C3C4=NC=CC=N4)=O)NC5=CC6=C(C=C5)NN=C6C7=CC=NC=C7 |
| Target Point | ERK1，2 |
| Passage | MAPK |
| Background | SCH772984 potently inhibits ERK1 and ERK2 activity. |
| Biological Activity | SCH772984 有效抑制 ERK1 和 ERK2 活性，IC50 分别为 4 和 1 nM。[1] |
| IC50 | ERK2:1nM;ERK1:4nM [1] |
| Data Literature Source | [1]. Morris EJ，et al. Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors. Cancer Discov. 2013 Jul;3(7):742-50. |
| Unit | Bottle |
| Specification | 2mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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