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Cyproterone Acetate

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Cat.No：IC3380 Solarbio

CAS：427-51-0

Molecular Formula：C24H29ClO4

Molecular Weight：416.94

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：≥98%

Appearance：White to off-white Solid

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Product Information

CAS	427-51-0
Name	Cyproterone Acetate
Molecular Formula	C24H29ClO4
Molecular Weight	416.94
Solubility	Soluble in DMSO≥10mg/mL；Soluble in Ethanol≥1mg/mL；Soluble in Water＜1mg/mL
Purity	≥98%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 207-048-3
MDL	MFCD00192402
SMILES	C[C@@]12C(C(Cl)=C[C@]3([H])[C@]2([H])C[C@@]4(C)[C@@]3([H])CC[C@]4(OC(C)=O)C(C)=O)=CC([C@H]5[C@@H]1C5)=O
InChIKey	UWFYSQMTEOIJJG-FDTZYFLXSA-N
InChI	InChI=1S/C24H29ClO4/c1-12(26)24(29-13(2)27)8-6-16-14-10-20(25)19-11-21(28)15-9-18(15)23(19,4)17(14)5-7-22(16,24)3/h10-11,14-18H,5-9H2,1-4H3/t14-,15+,16-,17-,18-,22-,23-,24-/m0/s1
PubChem CID	9880
Target Point	Androgen Receptor
Passage	Endocrinology & Hormones
Background	Cyproterone Acetate is an androgen receptor antagonist.
Biological Activity	是雄激素受体拮抗剂，IC50为7.1 nM，也是微弱的孕激素受体激动剂，具有微弱的孕激素和糖皮质激素活性。[1]
IC50	Androgen Receptor: 7.1nM [1]
Data Literature Source	[1] Sonneveld E，et al. Toxicol Sci. 2005，83(1)，136-148. [2] Attardi BJ，et al. Mol Cell Endocrinol. 2010，328(1-2)，16-21. [3] Arafa NM. Pak J Biol Sci. 2010，13(20)，966-976.
Unit	Bottle
Specification	50mg 100mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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