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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > SRT-2183CAS：1001908-89-9
Molecular Formula：C27H24N4O2S
Molecular Weight：468.57
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 1001908-89-9 |
| Name | SRT-2183 |
| Molecular Formula | C27H24N4O2S |
| Molecular Weight | 468.57 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | O=C(NC1=C(C2=CN3C(SC=C3CN4CC[C@@H](O)C4)=N2)C=CC=C1)C(C=C5)=CC6=C5C=CC=C6 |
| Target Point | Sirtuin |
| Passage | Cell Cycle;DNA Damage/DNA Repair; Epigenetics |
| Background | SRT2183 is a small molecule activator of the sirtuin protein isoform SIRT1. |
| Biological Activity | SRT 2183 is a selective Sirtuin-1 (SIRT1) activator with an EC1.5 value of 0.36 μM[1] |
| Data Literature Source | [1] Milne JC，et al. Nature. 2007，450(7170):712-6. [2] Anna Scuto，et al. Blood. 2009，114:3083. [3] Pacholec M，et al. J Biol Chem. 2010，285(11):8340-51. [4] Pacholec M，et al. J Biol Chem. 2010，285(11):8340-51. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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