{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > BGB-290CAS：1446261-44-4
Molecular Formula：C16H15FN4O
Molecular Weight：298.31
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
Qty：
Size：
| CAS | 1446261-44-4 |
| Name | BGB-290 |
| Molecular Formula | C16H15FN4O |
| Molecular Weight | 298.31 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD30489383 |
| SMILES | O=C1NN=C2CN(CCC3)[C@@]3(C)C(N4)=C2C5=C4C=C(F)C=C51 |
| Target Point | PARP |
| Passage | Cell Cycle;DNA Damage/DNA Repair; Epigenetics |
| Background | BGB-290 is a potent PARP1 and PARP2 selective inhibitor |
| Biological Activity | Pamiparib (BGB-290)是有效的PARP1和PARP2选择性抑制剂，IC50分别为0.83和0.11 nM。相较于其他PARP酶，它对PARP1和PARP2具有高选择性。[1] |
| IC50 | PARP1: 0.83nM;PARP2: 0.11nM [1] |
| Data Literature Source | [1] Zhiyu Tang，et al. AACR; Cancer Res. 2015，75(15 Suppl):Abstract nr 1653. [2] Zhiyu Tang，et al. AACR; Cancer Res 2015. 75(15 Suppl):Abst |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
