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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > DNA Damage & DNA Repai > PalifosfamideCAS：31645-39-3
Molecular Formula：C4H11Cl2N2O2P
Molecular Weight：221.02
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥97%
Appearance：White to off-white Solid
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| CAS | 31645-39-3 |
| Name | Palifosfamide |
| Molecular Formula | C4H11Cl2N2O2P |
| Molecular Weight | 221.02 |
| Solubility | Soluble in DMSO |
| Purity | ≥97% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD01705455 |
| SMILES | O=P(NCCCl)(NCCCl)O |
| Target Point | DNA Alkylator |
| Passage | DNA Damage/DNA Repair |
| Background | Palifosfamide is a novel DNA alkylating agent, the active metabolite of ifosfamide, with antitumor activity. |
| Biological Activity | Palifosfamide is a novel DNA alkylator and the active metabolite of ifosfamide， with antitumor activity.[1-2] |
| Data Literature Source | [1]. Hingorani P， et al. Preclinical activity of palifosfamide lysine (ZIO-201) in pediatric sarcomas including oxazaphosphorine-resistant osteosarcoma. Cancer Chemother Pharmacol. 2009 Sep;64(4):733-40. [2]. Jones B， et al. Anticancer activity of stabilized palifosfamide in vivo: schedule effects， oral bioavailability， and enhanced activity with docetaxel and doxorubicin. Anticancer Drugs. 2012 Feb;23(2):173-84. |
| Unit | Bottle |
| Specification | 2mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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