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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > 4-HydroxyquinazolineCAS：491-36-1
Molecular Formula：C8H6N2O
Molecular Weight：146.15
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 491-36-1 |
| Name | 4-Hydroxyquinazoline |
| Molecular Formula | C8H6N2O |
| Molecular Weight | 146.15 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 207-735-8 |
| MDL | MFCD00511302 |
| SMILES | O=C1NC=NC2=C1C=CC=C2 |
| Target Point | PARP inhibitor |
| Passage | Cell Cycle;DNA Damage/DNA Repair; Epigenetics |
| Background | 4-Hydroxyquinazoline has various physiological activities, such as antibacterial, antifungal, anticonvulsant, antiinflammatory, antiHIV, anticancer and analgesic activities. |
| Biological Activity | 4-hydroxyquinazoline (4-HQN), a potent PARP-1 inhibitor. [1] |
| Data Literature Source | [1]. Veres B，Radnai B，Gallyas F Jr，Varbiro G，Berente Z，Osz E，Sumegi B. Regulation of kinase cascades and transcription factors by a poly(ADP-ribose) polymerase-1 inhibitor，4-hydroxyquinazoline，in lipopolysaccharide-induced inflammation in mice. J Pharmacol Exp Ther. 2004 Jul;310(1):247-55. |
| Unit | Bottle |
| Specification | 100mg 200mg 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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