{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > MK-5108CAS：1010085-13-8
Molecular Formula：C22H21ClFN3O3S
Molecular Weight：461.94
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 1010085-13-8 |
| Name | MK-5108 |
| Molecular Formula | C22H21ClFN3O3S |
| Molecular Weight | 461.94 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD22124479 |
| SMILES | FC(C(Cl)=CC=C1)=C1O[C@H](CC2)CC[C@@]2(C(O)=O)CC3=CC=CC(NC4=NC=CS4)=N3 |
| Target Point | Aurora Kinase |
| Passage | Cell Cycle |
| Background | MK-5108 is a highly selective Aurora A inhibitor. |
| Biological Activity | MK-5108是高效和特异性的Aurora-A激酶抑制剂，IC50值为0.064 nM[1]。 |
| IC50 | Aurora A:64 pM [1] |
| Data Literature Source | [1]. Shimomura T，et al. MK-5108，a highly selective Aurora-A kinase inhibitor，shows antitumor activity alone and in combination with docetaxel. Mol Cancer Ther. 2010 Jan;9(1):157-66. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
