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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > FRAX-597CAS：1286739-19-2
Molecular Formula：C29H28ClN7OS
Molecular Weight：558.1
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 1286739-19-2 |
| Name | FRAX-597 |
| Molecular Formula | C29H28ClN7OS |
| Molecular Weight | 558.1 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD25976723 |
| SMILES | O=C1C(C2=CC=C(C3=CN=CS3)C=C2Cl)=CC4=CN=C(NC5=CC=C(N6CCN(C)CC6)C=C5)N=C4N1CC |
| Target Point | PAK1,2,3 |
| Passage | Cell Cycle; Cytoskeleton |
| Background | FRAX597 is a potent, ATP-competitive class 1 inhibitor of PAKs. |
| Biological Activity | FRAX597 是一种有效的PAK抑制剂，作用于 PAK1，2 和 3，IC50 分别为 8，13 和 19 nM[1]。 |
| Data Literature Source | [1]. Licciulli S，et al. FRAX597，a small molecule inhibitor of the p21-activated kinases，inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas. J Biol Chem. 2013 Oct 4;288(40):29105-14 |
| Unit | Bottle |
| Specification | 2mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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