{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > PI3K/Akt/mTOR > FimepinostatCAS：1339928-25-4
Molecular Formula：C23H24N8O4S
Molecular Weight：508.55
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Off-white to yellow Solid
Qty：
Size：
| CAS | 1339928-25-4 |
| Name | Fimepinostat |
| Molecular Formula | C23H24N8O4S |
| Molecular Weight | 508.55 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Off-white to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD22420823 |
| SMILES | O=C(C1=CN=C(N(CC2=CC3=NC(C4=CC=C(OC)N=C4)=NC(N5CCOCC5)=C3S2)C)N=C1)NO |
| Target Point | HDAC;PI3K |
| Passage | DNA Damage/DNA Repair;Epigenetics;NF-κB;PI3K/Akt/mTOR |
| Background | CUDC-907 is a dual inhibitor of PI3K and HDAC. |
| Biological Activity | Fimepinostat有效抑制 I 型 PI3K 及 I 和 II 型 HDAC 酶，作用于 PI3Kα/PI3Kβ/PI3Kδ 和 HDAC1/HDAC2/HDAC3/HDAC10 ，IC50 分别为 19/54/39 nM 和 1.7/5.0/1.8/2.8 nM[1]。 |
| Data Literature Source | [1]. Qian C，et al. Cancer network disruption by a single molecule inhibitor targeting both histone deacetylase activity and phosphatidylinositol 3-kinase signaling. Clin Cancer Res. 2012 Aug 1;18(15):4104-13. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
