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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > BAY-1217389CAS：1554458-53-5
Molecular Formula：C27H24F5N5O3
Molecular Weight：561.5
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1554458-53-5 |
| Name | BAY-1217389 |
| Molecular Formula | C27H24F5N5O3 |
| Molecular Weight | 561.5 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | O=C(NC1CC1)C2=CC=C(C3=CN=C4C(NCCC(F)(F)F)=CC(OC5=CC=C(OC)C(F)=C5F)=NN43)C=C2C |
| Target Point | Mps1 |
| Passage | Cell Cycle; Cytoskeleton |
| Background | BAY 1217389 Selective serine/threonine kinase monopolar spindle 1 (Mps1) inhibitor. |
| Biological Activity | BAY 1217389 is a potent， and selective inhibitor of the monopolar spindle 1 (MPS1) kinase with an IC50 value less than 10 nM.[1-2] |
| Data Literature Source | [1]. Wengner AM， et al. Novel Mps1 Kinase Inhibitors with Potent Antitumor Activity. Mol Cancer Ther. 2016 Apr;15(4):583-92.. . . . [2]. Wengner AM， et al. Novel Mps1 Kinase Inhibitors with Potent Antitumor Activity. Mol Cancer Ther. 2016 Apr;15(4):583-92. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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