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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > ARS-1620CAS：1698055-85-4
Molecular Formula：C21H17ClF2N4O2
Molecular Weight：430.84
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Off-white to yellow Solid
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| CAS | 1698055-85-4 |
| Name | ARS-1620 |
| Molecular Formula | C21H17ClF2N4O2 |
| Molecular Weight | 430.84 |
| Solubility | Soluble in DMSO ≥5mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Off-white to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD31619312 |
| SMILES | C=CC(N1CCN(C2=C3C=C(Cl)[C@@]([C@@]4=C(O)C=CC=C4F)=C(F)C3=NC=N2)CC1)=O.[S] |
| Target Point | K-Ras |
| Passage | Cell Cycle; GPCR & G Protein |
| Background | ARS-1620 is a potent covalent inhibitor of KRASG12C. |
| Biological Activity | ARS-1620 is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics.[1] |
| Data Literature Source | [1]. Janes MR， et al. Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor. Cell. 2018 Jan 25;172(3):578-589.e17. |
| Unit | Bottle |
| Specification | 2mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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