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GSK3787

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Cat.No：IG2030 Solarbio

CAS：188591-46-0

Molecular Formula：C₁₅H₁₂ClF₃N₂O₃S

Molecular Weight：392.78

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：≥98%

Appearance：White to off-white Solid

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Product Information

CAS	188591-46-0
Name	GSK3787
Molecular Formula	C₁₅H₁₂ClF₃N₂O₃S
Molecular Weight	392.78
Solubility	Soluble in DMSO
Purity	≥98%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
MDL	MFCD00099612
SMILES	O=C(NCCS(=O)(C1=NC=C(C(F)(F)F)C=C1)=O)C2=CC=C(Cl)C=C2
Target Point	PPAR
Passage	Cell Cycle;DNA Damage/DNA Repair;Metabolic Enzyme&Protease
Background	GSK3787 is a selective and irreversible peroxisome proliferator-activated receptor delta (PPARdelta) antagonist.
Biological Activity	GSK3787 是一种选择性和不可逆的过氧化物酶体增殖物激活受体 δ (PPARδ) 拮抗剂。
Data Literature Source	[1]. Shearer BG，et al. Identification and characterization of 4-chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787)，a selective and irreversible peroxisome proliferator-activated receptor delta (PPARdelta) antagonist. J Med Chem. 2010 Feb 25;53(4):1857-61. [2]. Palkar PS，et al. Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-beta/delta antagonist GSK3787. Mol Pharmacol. 2010 Sep;78(3):419-30.
Unit	Bottle
Specification	10mg 50mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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