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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Angiogenesis > PF-573228CAS：869288-64-2
Molecular Formula：C22H20F3N5O3S
Molecular Weight：491.49
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 869288-64-2 |
| Name | PF-573228 |
| Molecular Formula | C22H20F3N5O3S |
| Molecular Weight | 491.49 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD11519967 |
| SMILES | O=C1NC2=C(C=C(NC3=NC=C(C(F)(F)F)C(NCC4=CC=CC(S(=O)(C)=O)=C4)=N3)C=C2)CC1 |
| Target Point | FAK |
| Passage | Angiogenesis; Protein Tyrosine Kinase/RTK |
| Background | PF-573228 is a potent and selective FAK inhibitor. |
| Biological Activity | PF-573228是有效的和选择性的FAK抑制剂，对FAK纯化重组催化片段的IC50值为4 nM[1]。 |
| IC50 | 4nM(FAK)[1] |
| Data Literature Source | [1]. Slack-Davis JK，et al. Cellular characterization of a novel focal adhesion kinase inhibitor. J Biol Chem. 2007 May 18;282(20):14845-52. |
| Unit | Bottle |
| Specification | 10mg 10mM*1mL in DMSO |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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