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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Protein Tyrosine Kinase/PTK > TirbanibulinCAS：897016-82-9
Molecular Formula：C26H29N3O3
Molecular Weight：431.53
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 897016-82-9 |
| Name | Tirbanibulin |
| Molecular Formula | C26H29N3O3 |
| Molecular Weight | 431.53 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-258-5 |
| MDL | MFCD18633218 |
| SMILES | O=C(CC1=NC=C(C2=CC=C(OCCN3CCOCC3)C=C2)C=C1)NCC4=CC=CC=C4 |
| Target Point | Src |
| Passage | Protein Tyrosine Kinase/RTK |
| Background | It is a peptidomimetic Src inhibitor that targets the polypeptide substrate binding site of Src. |
| Biological Activity | KX2-391 是第一个进入临床的拟肽类Src抑制剂，靶向Src的多肽底物结合位点，对多种癌细胞株GI50为9-60 nM。[1-2] |
| Data Literature Source | [1]. Lau GM，et al. Expression of Src and FAK in hepatocellular carcinoma and the effect of Src inhibitors on hepatocellular carcinoma in vitro. Dig Dis Sci，2009，54(7)，1465-1474. [2]. Fallah-Tafti A，et al. Thiazolyl N-benzyl-substituted acetamide derivatives: synthesis，Src kinase inhibitory and anticancer activities. Eur J Med Chem，2011，46(10)，4853-4858. |
| Unit | Bottle |
| Specification | 5mg 10mM*1mL in DMSO 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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