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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Protein Tyrosine Kinase/PTK > 1-Naphthyl PP1CAS：221243-82-9
Molecular Formula：C19H19N5
Molecular Weight：317.39
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to brown Solid
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| CAS | 221243-82-9 |
| Name | 1-Naphthyl PP1 |
| Molecular Formula | C19H19N5 |
| Molecular Weight | 317.39 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Light yellow to brown Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD03425471 |
| SMILES | CC(N1N=C(C2=C3C=CC=CC3=CC=C2)C4=C(N)N=CN=C41)(C)C |
| InChIKey | XSHQBIXMLULFEV-UHFFFAOYSA-N |
| InChI | InChI=1S/C19H19N5/c1-19(2,3)24-18-15(17(20)21-11-22-18)16(23-24)14-10-6-8-12-7-4-5-9-13(12)14/h4-11H,1-3H3,(H2,20,21,22) |
| PubChem CID | 4877 |
| Target Point | Src;PKD |
| Passage | Protein Tyrosine Kinase/RTK;Apoptosis |
| Background | 1-Naphthyl PP1 is a selective src family kinase and Protein Kinase D inhibitor. 1-Naphthyl PP1 inhibits v-Src and c-Fyn, c-Abl, CDK2 and CAMK II. |
| Biological Activity | 1-Naphthyl PP1 (1-NA-PP 1) is a selective inhibitor of src family kinases. 1-Naphthyl PP1 inhibits v-Src and c-Fyn， c-Abl， CDK2 and CAMK II with IC50s of 1.0， 0.6， 0.6， 18 and 22 μM， respectively[1]. |
| Data Literature Source | [1]. Bishop AC，et al. A chemical switch for inhibitor-sensitive alleles of any protein kinase. Nature. 2000 Sep 21;407(6802):395-401. |
| Unit | Piece |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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