{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > CapecitabineCAS：154361-50-9
Molecular Formula：C15H22FN3O6
Molecular Weight：359.35
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 154361-50-9 |
| Name | Capecitabine |
| Molecular Formula | C15H22FN3O6 |
| Molecular Weight | 359.35 |
| Solubility | Soluble in Water/DMSO ≥10mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 604-948-1 |
| MDL | MFCD00930626 |
| SMILES | C[C@@H]1[C@H]([C@H]([C@H](N2C(N=C(C(F)=C2)NC(OCCCCC)=O)=O)O1)O)O |
| InChIKey | GAGWJHPBXLXJQN-UORFTKCHSA-N |
| InChI | InChI=1S/C15H22FN3O6/c1-3-4-5-6-24-15(23)18-12-9(16)7-19(14(22)17-12)13-11(21)10(20)8(2)25-13/h7-8,10-11,13,20-21H,3-6H2,1-2H3,(H,17,18,22,23)/t8-,10-,11-,13-/m1/s1 |
| PubChem CID | 60953 |
| Target Point | DNA/RNA Synthesis |
| Passage | Cell Cycle;DNA Damage/DNA Repair |
| Background | It is a fluoropyrimidine carbamate, which can be catalyzed by thymidine phosphorylase and converted into its active metabolite Fluorouracil (FU), which can be used for anti-tumor research. |
| Biological Activity | Capecitabine 是一种可用于口服的前药，可由胸苷磷酸化酶催化转变为其活性代谢物 Fluorouracil (FU)。[1-2] |
| Data Literature Source | [1]. PharmD CM，et al. Capecitabine: A review. Clinical Therapeutics. 2005 Jan; 27(1): 23-44. [2]. Guichard SM，et al. Gene expression predicts differential capecitabine metabolism，impacting on both pharmacokinetics and antitumour activity. Eur J Cancer. 2008 Jan;44(2):310-7. |
| Unit | Piece |
| Specification | 100mg 10mM*1mL in DMSO 10mM*1mL in Water 200mg 500mg 1g |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Capecitabine Can Induce T Cell Apoptosis: A Potential Immunosuppressive Agent With Anti-Cancer Effect
Click to check >>Author：Zhang S; Wang Z; Fan S; Liu T; Yoshida S; Yang S;
IF：7.3000
Publish_to：Front Immunol
PMID：34557199
Manual Download
