{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > PI3K/Akt/mTOR > CCT 128930CAS：885499-61-6
Molecular Formula：C18H20ClN5
Molecular Weight：341.84
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Off-white to yellow Solid
Qty：
Size：
| CAS | 885499-61-6 |
| Name | CCT 128930 |
| Molecular Formula | C18H20ClN5 |
| Molecular Weight | 341.84 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Off-white to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | ClC1=CC=C(C=C1)CC2(CCN(CC2)C3=NC=NC4=C3C=CN4)N |
| InChIKey | RZIDZIGAXXNODG-UHFFFAOYSA-N |
| InChI | InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)11-18(20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23) |
| PubChem CID | 17751819 |
| Target Point | Akt |
| Passage | PI3K/Akt/mTOR |
| Background | CCT128930 is a potent and selective Akt2 inhibitor |
| Biological Activity | CCT128930 是一种有效的选择性 Akt2 抑制剂 (IC50 为 6 nM)，比作用于 PKA 激酶 (IC50 为 168 nM) 选择性高 28 倍，比作用于 p70S6K (IC50 为 120 nM) 选择性高 20 倍[1]。 |
| IC50 | Akt2:6nM p70S6K:120nM PKA:168nM [1] |
| Data Literature Source | [1]. Yap TA et al. Preclinical pharmacology，antitumor activity，and development of pharmacodynamic markers for the novel，potent AKT inhibitor CCT128930. Mol Cancer Ther. 2011 Feb;10(2):360-71 |
| Unit | Piece |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
