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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > DehydroevodiamineCAS：67909-49-3
Molecular Formula：C19H15N3O
Molecular Weight：301.34
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 67909-49-3 |
| Name | Dehydroevodiamine |
| Molecular Formula | C19H15N3O |
| Molecular Weight | 301.34 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-258-5 |
| MDL | MFCD11656140 |
| SMILES | O=C1N2C(C([N-]C3=C4C=CC=C3)=C4CC2)=[N+](C)C5=C1C=CC=C5 |
| Target Point | Others |
| Passage | Others |
| Background | Dehydroevodiamine is a quinazoline alkaloid in Evodiae Fructus. |
| Biological Activity | Dehydroevodiamine 是从吴茱萸 Evodiae Fructus 中分离出的喹唑啉生物碱，对豚鼠心室肌细胞具有抗心律失常作用。Dehydroevodiamine 抑制 LPS 诱导的小鼠巨噬细胞中 iNOS，COX-2，前列腺素E2 (PGE2) 和核因子-κB (NF-κB) 的表达。[1-2] |
| Data Literature Source | [1]. Loh SH，et al. Antiarrhythmic effects of dehydroevodiamine in isolated human myocardium and cardiomyocytes. J Ethnopharmacol. 2014 May 14;153(3):753-62. [2]. Noh EJ，et al. Inhibition of lipopolysaccharide-induced iNOS and COX-2 expression by dehydroevodiamine through suppression of NF-kappaB activation in RAW 264.7 macrophages. Life Sci. 2006 Jul 10;79(7):695-701. Epub 2006 Mar 6. |
| Unit | Bottle |
| Specification | 5mg 10mg 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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