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My CartCAS：564-25-0
Molecular Formula：C22H24N2O8
Molecular Weight：444.44
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 564-25-0 |
| Name | Doxycycline |
| Molecular Formula | C22H24N2O8 |
| Molecular Weight | 444.44 |
| Solubility | Soluble in DMSO ≥5mg/mL;Soluble in Water ≥5mg/mL(Need ultrasonic or add NaOH to help dissolve) |
| Purity | HPLC≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 209-271-1 |
| MDL | MFCD00800994 |
| SMILES | O=C(C1=C(O)[C@@H](N(C)C)[C@@]([C@@H](O)[C@@]2([H])C(C(C3=C(O)C=CC=C3[C@@H]2C)=O)=C4O)([H])[C@@]4(O)C1=O)N |
| Target Point | Antibiotic;MMP |
| Passage | Anti-infection |
| Background | Doxycycline is a tetracycline antibiotic and a broad-spectrum metalloproteinase (MMP) inhibitor. |
| Biological Activity | Doxycycline 是一种四环素抗生素，口服有效的，广谱的金属蛋白酶 (MMP) 抑制剂，具有抗菌活性。[1-2] |
| Data Literature Source | [1]. Briest W，et al. Doxycycline ameliorates the susceptibility to aortic lesions in a mouse model for the vascular type of Ehlers-Danlos syndrome. J Pharmacol Exp Ther. 2011 Jun;337(3):621-7. [2]. Luger AL，et al. Doxycycline Impairs Mitochondrial Function and Protects Human Glioma Cells from Hypoxia-Induced Cell Death: Implications of Using Tet-Inducible Systems. Int J Mol Sci. 2018 May 17;19(5) |
| Unit | Bottle |
| Specification | 10mg 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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