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AmLodipine

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Cat.No：IA2340 Solarbio

CAS：88150-42-9

Molecular Formula：C₂₀H₂₅ClN₂O₅

Molecular Weight：408.88

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：White to off-white Solid

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Product Information

CAS	88150-42-9
Name	AmLodipine
Molecular Formula	C₂₀H₂₅ClN₂O₅
Molecular Weight	408.88
Solubility	Soluble in DMSO ≥5mg/mL
Purity	HPLC≥98%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Delivery Time	1-2 Days
EC	EINECS 1308068-626-2
MDL	MFCD00864687
SMILES	O=C(C1=C(COCCN)NC(C)=C(C(OC)=O)C1C2=CC=CC=C2Cl)OCC
InChIKey	HTIQEAQVCYTUBX-UHFFFAOYSA-N
InChI	InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3
PubChem CID	2162
Target Point	Calcium Channel
Passage	Membrane Transporter&Ion Channel;Neuronal Signaling
Background	AmLodipine is a long-acting calcium blocker.
Biological Activity	Amlodipine (UK-48340) 是一种长效的钙离子通道抑制剂，用于降低血压缓解胸部疼痛。Amlodipine也以剂量依赖性方式抑制自由基引起的膜中的脂质成分的损伤。[1-6]
Data Literature Source	[1] Zhang X，et al. Circulation，1998，97(6)，576-580. [2] Mason RP，et al. J Mol Cell Cardiol，1999，31(1)，275-281. [3] Nussberger J，et al. Hypertension，2008，51(5)，1306-1311. [4] Mason RP，et al. J Neurochem，1999，72(4)，1448-1456. [5] Sharifi AM，et al. J Hypertens，1998，16(4)，457-466. [6] Zhou MS，et al. Am J Hypertens，2004，17(2)，167-171.
Unit	Bottle
Specification	100mg 10mM*1mL in DMSO 200mg 500mg 1g

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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