Balaglitazone
Cat.No:IB1020 Solarbio
CAS:199113-98-9
Molecular Formula:C20H17N3O4S
Molecular Weight:395.43
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:Light yellow to yellow Solid
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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > BalaglitazoneCAS:199113-98-9
Molecular Formula:C20H17N3O4S
Molecular Weight:395.43
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:Light yellow to yellow Solid
Qty:
Size:
| CAS | 199113-98-9 |
| Name | Balaglitazone |
| Molecular Formula | C20H17N3O4S |
| Molecular Weight | 395.43 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
| Delivery Time | 1-2 Days |
| MDL | MFCD09837808 |
| SMILES | O=C(N1)SC(CC2=CC=C(OCC(N3C)=NC4=C(C=CC=C4)C3=O)C=C2)C1=O |
| InChIKey | IETKPTYAGKZLKY-UHFFFAOYSA-N |
| InChI | InChI=1S/C20H17N3O4S/c1-23-17(21-15-5-3-2-4-14(15)19(23)25)11-27-13-8-6-12(7-9-13)10-16-18(24)22-20(26)28-16/h2-9,16H,10-11H2,1H3,(H,22,24,26) |
| PubChem CID | 9889200 |
| Target Point | PPAR |
| Passage | Cell Cycle;DNA Damage/DNA Repair;Metabolic Enzyme&Protease |
| Background | Balaglitazone/DRF-2593 is a selective PPARγ agonist |
| Biological Activity | Balaglitazone is a selective partial PPARγ agonist with an EC50 of 1.351 μM for human PPARγ.[1-3] |
| Data Literature Source | [1]. Larsen PJ, et al. Dissociation of antihyperglycaemic and adverse effects of partial perioxisome proliferator-activated receptor (PPAR-gamma) agonist balaglitazone. Eur J Pharmacol. 2008 Oct 31;596(1-3):173-9. [2]. Yousefi B, et al. Balaglitazone reverses P-glycoprotein-mediated multidrug resistance via upregulation of PTEN in a PPARγ-dependent manner in leukemia cells. Tumour Biol. 2017 Oct;39(10):1010428317716501. [3]. Henriksen K, et al. A comparison of glycemic control, water retention, and musculoskeletal effects of balaglitazone and pioglitazone in diet-induced obese rats. Eur J Pharmacol. 2009 Aug 15;616(1-3):340-5. |
| Unit | Piece |
| Specification | 5mg 10mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
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