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My CartCAS：39809-25-1
Molecular Formula：C10H15N5O3
Molecular Weight：253.26
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
Qty：
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| CAS | 39809-25-1 |
| Name | Penciclovir |
| Molecular Formula | C10H15N5O3 |
| Molecular Weight | 253.26 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 663-371-3 |
| MDL | MFCD00866931 |
| SMILES | O=C1NC(N)=NC2=C1N=CN2CCC(CO)CO |
| InChIKey | JNTOCHDNEULJHD-UHFFFAOYSA-N |
| InChI | InChI=1S/C10H15N5O3/c11-10-13-8-7(9(18)14-10)12-5-15(8)2-1-6(3-16)4-17/h5-6,16-17H,1-4H2,(H3,11,13,14,18) |
| PubChem CID | 135398748 |
| Target Point | HSV |
| Passage | Anti-infection |
| Background | Penciclovir is effective against HSV1 and 2. |
| Biological Activity | Penciclovir 有效作用于 HSV1 和 2，IC50 分别为 0.04-1.8 μg/mL 和 0.06-4.4 μg/mL。[1-2] |
| IC50 | 0.04-1.8μg/mL(HSV-1)，0.06-4.4μg/mL(HSV-2)，1.6-8μg/mL(VZV)，1.5-3.1μg/mL(EBV)，51μg/mL(HCMV)[1] |
| Data Literature Source | [1]. Piret J，et al. Resistance of herpes simplex viruses to nucleoside analogues: mechanisms，prevalence，and management. Antimicrob Agents Chemother. 2011 Feb;55(2):459-72. [2]. Xiong Z，et al. Imaging chemically modified adenovirus for targeting tumors expressing integrin alphavbeta3 in living micewith mutant herpes simplex virus type 1 thymidine kinase PET reporter gene. J Nucl Med. 2006 Jan;47(1):130-9. |
| Unit | Bottle |
| Specification | 50mg 100mg 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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