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My CartCAS：1266084-51-8
Molecular Formula：C17H14BF4NO3
Molecular Weight：367.1
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1266084-51-8 |
| Name | Acoziborole |
| Molecular Formula | C17H14BF4NO3 |
| Molecular Weight | 367.1 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | O=C(NC1=CC=C2C(C)(C)OB(O)C2=C1)C3=CC=C(F)C=C3C(F)(F)F |
| Target Point | Parasite |
| Passage | Anti-infection |
| Background | Acoziborole is a compound with potent anti-trypanosome activity |
| Biological Activity | Acoziborole (SCYX-7158) is an effective， safe and orally active antiprotozoal agent for the research of human african trypanosomiasis (HAT). In the T. b. brucei S427 strain， the MIC value for SCYX-7158 is 0.6 μg/mL[1]. |
| Data Literature Source | [1]. Jacobs RT，et al. SCYX-7158，an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis. PLoS Negl Trop Dis. 2011 Jun;5(6):e1151. |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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