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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > AcemetacinCAS：53164-05-9
Molecular Formula：C21H18ClNO6
Molecular Weight：415.82
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 53164-05-9 |
| Name | Acemetacin |
| Molecular Formula | C21H18ClNO6 |
| Molecular Weight | 415.82 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 258-403-4 |
| MDL | MFCD00151473 |
| SMILES | O=C(OCC(O)=O)CC1=C(C)N(C(C2=CC=C(Cl)C=C2)=O)C3=C1C=C(OC)C=C3 |
| InChIKey | FSQKKOOTNAMONP-UHFFFAOYSA-N |
| InChI | InChI=1S/C21H18ClNO6/c1-12-16(10-20(26)29-11-19(24)25)17-9-15(28-2)7-8-18(17)23(12)21(27)13-3-5-14(22)6-4-13/h3-9H,10-11H2,1-2H3,(H,24,25) |
| PubChem CID | 1981 |
| Target Point | COX |
| Passage | Immunology & Inflammation |
| Background | Acemetacin is a non-steroidal anti-inflammatory compound. |
| Biological Activity | Acemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.[1] |
| IC50 | COX-1: 85μM(in human intact cell)[1] |
| Data Literature Source | [1]. Tavares IA，et al. Non-steroidal anti-inflammatory drugs that cause relatively little gastric damage. J Gastroenterol Hepatol. 1998 Nov;13(S3):S190-S192. |
| Unit | Bottle |
| Specification | 500mg 5g 1g |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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