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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > 6-MercaptopurineCAS：50-44-2
Molecular Formula：C5H4N4S
Molecular Weight：152.18
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥99%
Appearance：Light yellow to yellow Solid
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| CAS | 50-44-2 |
| Name | 6-Mercaptopurine |
| Molecular Formula | C5H4N4S |
| Molecular Weight | 152.18 |
| Solubility | Soluble in DMSO |
| Purity | ≥99% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-037-4 |
| MDL | MFCD00599524 |
| SMILES | S=C1NC=NC2=C1NC=N2 |
| InChIKey | GLVAUDGFNGKCSF-UHFFFAOYSA-N |
| InChI | InChI=1S/C5H4N4S/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10) |
| PubChem CID | 667490 |
| Target Point | DNA/RNA Synthesis inhibitor |
| Passage | Cell Cycle;DNA Damage/DNA Repair |
| Background | 6-Mercaptopurine is a purine analog and an antagonist of endogenous purines |
| Biological Activity | 6-Mercaptopurine 是一种嘌呤类似物，是内源性嘌呤的拮抗剂且已被广泛用作抗白血病药物和免疫抑制药物。[1-3] |
| Data Literature Source | [1]. Sahasranaman S， et al. Clinical pharmacology and pharmacogenetics of thiopurines. Eur J Clin Pharmacol. 2008 Aug; 64 (8) :753-67. [2]. Liu Q， et al. 6-Mercaptopurine augments glucose transport activity in skeletal muscle cells in part via a mechanism dependent upon orphan nuclear receptor NR4A3. Am J Physiol Endocrinol Metab. 2013 Nov 1; 305 (9) :E1081-92. [3]. Kanemitsu H， et al. 6-Mercaptopurine (6-MP) induces cell cycle arrest and apoptosis of neural progenitor cells in the developing fetal rat brain. Neurotoxicol Teratol. 2009 Mar-Apr; 31 (2) :104-9 |
| Unit | Bottle |
| Specification | 50mg 100mg 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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